The peanut patch trial was conducted at five research sites: Arkansas Children's Hospital, the National Jewish Health Center in Denver, Johns Hopkins University, the Icahn School of Medicine at Mount Sinai and the University of North Carolina at Chapel Hill School of Medicine.
Before the trial began, researchers assessed each volunteer's peanut allergy via an oral food challenge with food containing peanuts. The median amount of nuts tolerated, before having allergic symptoms was about one-seventh of a peanut, according to Dr. Stacie M. Jones, chief of allergy and immunology at Arkansas Children's Hospital and the study lead.
After establishing an allergy baseline, the participants were given quarter-size patches on the insides of their upper arms for adolescents, or on their backs for younger kids.
The patches were administered daily for the 52-week period, but Jones said placement varied in order to allow any skin irritation to heal.
About 80% of the kids who used peanut patches (both low- and high-dose strength) had some reaction, Jones said, but they were mainly mild, like bumps and redness on the skin surrounding the patch.
Hailey Middlebrook, CNN
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